A Boy with Adrenocortical Tumor Who Progressed to Central Precocious Puberty after Surgery.

Chueh,  Hee Won; Bak,  Nu Ri; Kim,  Myo Jing; Yoo,  Jae Ho; Rho,  Mi Sook; Cho,  Won Yeol

doi:2012.17.1.57

Ann Pediatr Endocrinol Metab > Volume 17(1); 2012 > Article

Case Report

Annals of Pediatric Endocrinology & Metabolism 2012;17(1): 57-61.

DOI: https://doi.org/10.6065/apem.2012.17.1.57

A Boy with Adrenocortical Tumor Who Progressed to Central Precocious Puberty after Surgery.

Hee Won Chueh, Nu Ri Bak, Myo Jing Kim, Jae Ho Yoo, Mi Sook Rho, Won Yeol Cho

¹Department of Pediatrics, Dong-A University College of Medicine, Busan, Korea. pedendo@dau.ac.kr
²Department of Surgical Pathology, Dong-A University College of Medicine, Busan, Korea.
³Department of Urology, Dong-A University College of Medicine, Busan, Korea.

Abstract

Adrenocortical tumors in children are rare and show various clinical symptoms. We present an 8-year-old boy with peripheral precocious puberty caused by adrenocortical tumor. He showed elevated serum DHEA-S and 17-hydroxyprogesterone, and computed tomography revealed an abdominal mass. After surgical resection, he developed central precocious puberty. We report a rare case that showed progression from peripheral precocious puberty to central precocious puberty.

Keywords: Adrenal cortex neoplasms;Child;Puberty, precocious