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Ann Pediatr Endocrinol Metab > Volume 14(1); 2009 > Article
Hyperglycemic Hyperosmolar State in Children with Type 2 Diabetes Mellitus: A Report of Two Cases.
Tae Yeon Kim, Jung Ahn, Hae Soon Kim
Department of Pediatrics, School of Medicine, Ewha Womans University, Seoul, Korea. hyesk@ewha.ac.kr
Hyperglycemic hyperosmolar state (HHS) is usually associated with type 2 diabetes mellitus (T2DM) with signigicant mortality and morbidity and is rare in pediatric population. The incidence of obesity and T2DM in children and adolescents is increasing at an alarming rate. With increasing rates of T2DM, the incidence of HHS may increase in pediatric population. HHS is characterized by severe hyperglycemia, a marked increase in serum osmolarity and clinical evidence of dehydration. The significance of HHS in children and adolescents remains largely unappreciated. We describe two obese adolescents with hyperglycemic hyperosmolar state at the onset of T2DM.
Keywords: Hyperglycemic hyperosmolar nonketotic coma;Type 2 diabetes mellitus;Children


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