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Ann Pediatr Endocrinol Metab > Volume 16(3); 2011 > Article
DOI: https://doi.org/10.6065/jkspe.2011.16.3.189   
Pamidronate Treatment in 9-Year-Old Boy Diagnosed with Gorham Disease.
Ju Young Yoon, Ji Eun Lee, Seung Wan Park, Min Jae Kang, Young Ah Lee, Sei Won Yang, Kyung Duk Park, Choong Ho Shin
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. chshinpd@snu.ac.kr
Gorham disease is a rare disorder characterized by proliferation of vascular channels resulting in destruction and resorption of osseous matrix. There is no standard treatment defined for this disease, and variable therapies such as medical, surgical, and radiation therapy have been used. Antiresorptive medication, such as bisphosphonate, is used in Gorham disease because they suppress the course of osteolysis and angiogenisis. We report a 9-year-old boy with Gorham disease, who was presented with recurrent hemothorax and treated by pamidronate. After treatment, he showed no recurrence of hemothorax for more than 2 years.
Keywords: Osteolysis, essential;Pamidronate;Child


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