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Ann Pediatr Endocrinol Metab > Volume 7(1); 2002 > Article
A Case of Cerebral Gigantism(Sotos Syndrome).
Sang Bum Kim, Seung Yang, Hong Dae Kim, Phil Soo Oh, Jae Kook Cha, Jeh Hoon Shin
Abstract
Cerebral gigantism(Sotos syndrome) is a growth disorder that consists of large size at birth, rapid early growth rate with accompanying advanced bone age, acromegalic features, and developmental delay. Clumsiness in the absence of other abnormal neurologic findings is common. The cause is unknown. We report here a case of 238/12-year-old Sotos syndrome with final adult height above 97 percentile, abnormal brain MRI findings(large ventricles, prominent trigone, prominent occipital horn & thining of corpus callosum), clumsiness, and some behavioral problems.
Keywords: Cerebral Gigantism;Sotos syndrome


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