Multifocal Brain Infarction and Intraventricular Hemorrhage in an Infant during Treatment of Diabetic Ketoacidosis.

Son,  Kyung Ran; Kim,  Joon Sung; Lee,  Hwa Yun; Noh,  Ha Young; Back,  Hee Jo; Woo,  Young Jong

Ann Pediatr Endocrinol Metab > Volume 7(2); 2002 > Article

Case Report

Journal of Korean Society of Pediatric Endocrinology 2002;7(2): 225-229.

Multifocal Brain Infarction and Intraventricular Hemorrhage in an Infant during Treatment of Diabetic Ketoacidosis.

Kyung Ran Son, Joon Sung Kim, Hwa Yun Lee, Ha Young Noh, Hee Jo Back, Young Jong Woo

Abstract

Fatal complications including cerebral edema and neurologic collapse occur during treatment of diabetic ketoacidosis(DKA). A 6-week-old female infant with fever, dehydration and drowsy mental status was diagnosed as DKA and neurologically deteriorated during treatment. The cranial computed tomography scan revealed multifocal brain infarctions of the left caudate nucleus, bilateral frontal periventricular white matter, and right parietal cortex. A moderate amount of hemorrhage was also noted in both lateral ventricles. She recovered rapidly with supportive treatment over time. The clinical course and radiologic findings of this patient emphasize the importance of brain infarction as a cause of persistent neurologic loss in children with DKA.

Keywords: Diabetic ketoacidosis;Brain infarction;Neonatal diabetes mellitus