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Ann Pediatr Endocrinol Metab > Volume 8(1); 2003 > Article
Giant Follicular Ovarian Cyst with Torsion in Juvenile Primary Hypothyroidism.
Jung Won Lee, Hyun Jin Kim, Hae Soon Kim
Abstract
Multicystic ovary was first described by Silver in 1958 as a rare case feature of acquired primary hypothyroidism. In 1980, Lindsay reported four girls with hypothyroidism associated with multicystic ovary diagnosed by pelvic ultrasonography. The mechanism of ovarian cyst formation and pseudoprecocious puberty in severe hypothyroidism in childhood are unknown. Increased ovarian sensitivity to GnRH and increased TSH level which acts on FSH receptor is one of the mechanism explained. We report a case of a girl with primary hypothyroidism presented with pseudoprecocious puberty and giant follicular ovarian cyst with torsion.
Keywords: Ovarian cyst;Hypothyroidism;Precocoius puberty


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