Original Article

J Korean Soc Pediatr Endocrinol. 2002; 7(1): 69-76.

Frequencies and Risk Factors for Microvascular Complications in Patients with Type 1 Diabetes Mellitus.

Mi Rang Lim, Young Lim Shin, and Han Wook Yoo

PURPOSE
This study was undertaken to identify the frequencies and the risk factors of microvascular complications in subjects with type 1 diabetes mellitus METHODS: The frequencies and their relation to risk factors of microvascular complications were analyzed in 29 type 1 diabetes mellitus subjects with duration of disease more than 5 years. Microvascular disease was defined as the presence of either retinopathy, microalbuminuria or neuropathy.
RESULTS
The overall prevalence rate of microvascular disease was 8/29(27.6%). Retinopathy has developed in 3 patients(10.3%), microalbuminuria in 7 patients(24.0 %) and neuropathy in 5 patients(17.2%). The mean HbA1C was significantly higher in the patients with microvascular complications(11.6+/-.2% in microvascular complication group vs 9.3+/-.6% in control group).
CONCLUSION
In childhood onset type 1 diabetes mellitus, poor glycemic control is an important risk factor for microvascular complications.

Keywords : Type 1 Diabetes Mellitus(IDDM), Microvascular complications, Retinopathy, Nephropathy, Neuropathy, Risk factors