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J Korean Soc Pediatr Endocrinol Search


Ann Pediatr Endocrinol Metab > Volume 5(2); 2000 > Article
A Case of Neonatal Diabetes Mellitus: Transient or Permanent?.
Dae Yeol Lee, Ho Keun Yi, Pyoung Han Hwang
A case of neonatal diabetes mellitus is described. The child presented with low birth weight but was normal in appearance. She was acidotic and ketonuria was observed. The HLA typing was DR1 and 3, and insulin autoantibodies were negative. Genetic analysis with polymorphic DNA markers for chromosome 6 indicated biparental inheritance. She required insulin therapy for the control of hyperglycemia, and insulin dependence continues after 8 months of age.
Keywords: Neonatal diabetes mellitus;Polymorphic DNA marker;Chromosome 6;Biparental inheritance


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