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Ann Pediatr Endocrinol Metab > Volume 17(2); 2012 > Article
DOI: https://doi.org/10.6065/apem.2012.17.2.113   
A Case of Extreme Uterine Hypotrophy in Hypogonadotropic Hypogonadism with Partial GH Deficiency.
Se Ra Min, Young Kwang Choo, Hyun Seok Cho, Hyeon Soo Lee, Ja Kyoung Kim, Hyang Ah Lee, Sung Yeon Ahn
1Department of Pediatrics, Kangwon National University School of Medicine, Chuncheon, Korea. ahn74@kangwon.ac.kr
2Department of Obstetrics and Gynecology, Kangwon National University School of Medicine, Chuncheon, Korea.
Abstract
Congenital hypogonadotropic hypogonadism is one of the causes of pubertal failure and primary amenorrhea, it is related to uterine hypotrophy. If the uterus is extremely hypotrophied, it is difficult to identify in imaging studies and can be misdiagnosed as a structural anomaly of internal genitalia. We report a case of extreme uterine hypotrophy in 18-year-old girl with primary amenorrhea that was finally diagnosed as hypogonadotrophic hypogonadism. The patient was initially suspected of Mullerian agenesis owing to the invisible uterus. After 4 months of treatment with estrogen, she showed significant growth of the uterus.
Keywords: Uterus;Growth;Amenorrhea;Hypogonadism


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